Back to catalog
GABA signaling research
3α-DHP Nasal Spray
40mg, 0.5mg per spray
A neuroactive steroid metabolite of progesterone.
Overview
3α-DHP (Allopregnanolone) is a neurosteroid that acts as a positive allosteric modulator of GABA-A receptors. It is studied for its role in mood regulation and neuro-endocrine signaling.
Mechanism of action
It binds specifically to the GABA-A receptor to enhance GABAergic inhibition.
Dosage & concentration
40 mg total; 0.5 mg per spray.
Storage & handling
Store in a cool, dark place.
Research & studies
- Tolerance to allopregnanolone with focus on the GABA-A receptor.Br J Pharmacol · 2011
- Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol.Eur J Pharmacol · 2004
- Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone.Brain Res Brain Res Rev · 2001